Functional Description MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide studied for its role in cellular energy regulation, metabolic signaling, and adaptive responses to metabolic stress. In research settings, MOTS-c is commonly investigated for its potential influence on glucose metabolism, insulin-related signaling, mitochondrial function, AMPK-associated pathways, and cellular energy homeostasis. […]